Our Focus

Basic Research


Basic Pain Research

To date, acute and chronic pain treatments have been commonly researched on the clinical basis. However, interests in basic research raised as the understanding in nociceptive processing has immensely increased in the past years. Basic research also allows more opportunities to discover preventative measures for chronic pain development, for instance,  in discoveries of pain-related transmission pathways mediating drugs.
 
Establishment of CPIP Model using a rubber O-ring.
 
 
Pain assessments for mechanical allodynia and thermal allodynia of a rat.
 
 
Complex regional pain syndrome (CPRS) is a concerned and recently incurable chronic neuropathic pain disorder, which maintenance is found to involve a molecule, endothelin-1 (ET-1) in the central nervous system. Two models are primarily used to mimic this disorder. The chronic post-ischemia pain (CPIP) model, is established by a prolonged hindlimb ischemia and reperfusion in the hindlimbs of the animals.

 

Pain Assessments Facilities

To manifest the effects of different experimental conditions on the acute and pain establishments, we are well-equipped with different standardized testing equipments and facilities for pain behavioral assessments on different pain mechanisms including mechanical allodynia, cold allodynia, and thermal hyper/hypoalgesia.